Trastornos psiquiátricos frecuentes post infarto agudo al miocardio y su relación pronóstica. Revisión de la literatura.

Manuel Mallol Simmonds

Resumen


La enfermedad cardiovascular es la principal causa de muerte a nivel mundial. De ella, el Infarto Agudo al Miocardio (IAM) y el Accidente Cerebrovascular (AVC) se encuentran fuertemente asociados a los cambios ambientales y sociales del último tiempo, tales como aumento de ingesta de comida rápida, sedentarismo, tabaquismo, entre otros. Algunos trastornos psiquiátricos que aparecen a corto y largo plazo posterior al evento coronario agudo tienen una implicancia directa en la morbimortalidad cardiovascular y global. De ellos, la depresión representa el trastorno psiquiátrico más frecuente, pudiendo encontrarse en 3 de cada 10 pacientes que tuvieron un IAM. La depresión aumenta las hospitalizaciones, disminuye la adherencia terapéutica y empeora el pronóstico cardiovascular a largo plazo.  La fisiopatología en lo anterior es explicada en parte por alteraciones en el eje neuroendocrino y la respuesta al estrés, mientras que otros fenómenos permanecen aún desconocidos. Dentro de otros trastornos psiquiátricos asociados a un IAM se encuentran el delirium, ansiedad y trastornos de la personalidad. En función de lo anterior, se hace necesaria la incorporación de un sistema continuo de monitoreo y apoyo en salud mental en este grupo de pacientes para mejorar tanto su pronóstico como la calidad de vida.

Palabras clave


Infarto al miocardio; Enfermedad Cardiovascular; Depresión; Trastornos psiquiátricos; Delirium; Salud y ambiente

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Referencias


Aguilar VB, Ochiai ME, Cardoso JN, Del Carlo CH, Morgado PC, Munhoz RT (2010). Relationship between depression, BNP levels and ventricular impairment in heart failure. Arquivos Brasileiros de Cardiología 95, 732-737.

Alhurani A, Lennie T, Moser D (2015). Predisposing Factors of Persistent Symptoms of Depression and Anxiety Among Patients With Acute Coronary Syndrome. Circulation 132, a18551

Arnold SV, Smolderen KG, Buchanan DM, Li Y, Spertus JA (2012). Perceived Stress in Myocardial Infarction. Journal of the American College of Cardiology 60, 1756-1763

Bancalero C, Aguilera A, Navarro M, Carrión L, Quirós A, Ruiz S (2013). Fundamentos teóricos de la intervención psiquiátrica y psicológica de enlace en unidades de rehabilitación cardiaca. C. Med. Psicosom 105, 20-30

Benyamini Y, Roziner I, Goldbourt U, Drory Y, Gerber Y (2013). Israel Study Group on First Acute Myocardial Infaction. Depression and Anxiety Following Myocardial Infarction and Their Inverse Associations with Future Health Behaviors and Quality of Life. Ann. Behav. Med. 46, 310-321

Berkman L, Blumenthal J, Burh M, Carney R, Catellier D, Czajkowski S, De-Busk R, Hosking J, Jaffe A, Mitches P, Norman J, Powell L, Schneiderman N, Gables C (2003). Effects of Treating Depression and Low Perceived Social Support on Clinical Events After Myocardial Infarction. The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA 289, 3106-3116

Blumel B, Gibbons A, Kanacri A, Kerrigan N, Florenzano R (2005). Depressive symptoms after an acute myocardial infarction. Revista Médica de Chile 133, 1021-1027.

Cabrera J, Gandarilla JC, González I (2011). Nuevos aspectos fisiopatológicos en la intervención psicosocial de las personas con enfermedad arterial coronaria. Revista Cubana de Medicina. 50, 83-93

Calderón J, Gabrielli L, Gonzalez M, Villarroel L, Castro P, Corbalán R (2010). Depressive Symproms Among Patients with acute myocardial infarction. Relationship with revascularization therapy. Revista Médica de Chile 138, 710-706.

Carney R, Blumenthal J, Freedland K, Youngblood M, Veith R, Burg M, Cornell C, Saab P, Kaufman P, Czajkowski S, Jaffe A (2004). Depression and Late Mortality After Myocardial Infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) Study. Psychosomatic Medicine 66, 466-474

Davidson K, Burg M, Kronish I, Shimbo D, Dettenborn L, Mehran R, Vorchheimer D, Clemow L, Schwartz J, Lesperance F, Rieckman N (2010). Association of Anhedonia With Recurrent Major Adverse Cardiac Events and Mortality 1 Year After Acute Coronary Syndrome. Archives of General Psychiatry 67, 480-488

Dawood T, Lambert E, Barton D, Laude D, Elghozi JL, Esler M, Haikerwal D, Kaye D, Hotchkin E, Lambert G (2007). Specific Serotonin Reuptake Inhibition in Major Depressive Disorder Adversely Affects Novel Markers of Cardiac Risk. Hypertension Research 4, 285-293

Deepti Kukreja, Ulf Gunther, Julius Popp (2015). Delirium in the elderly: current problems with increasing geriatric age. Indian Journal of Medical Research 142, 655-662.

Feinkohl I, Sattar N, Welsh P, Reynolds RM, Deary IJ, Strachan MW (2017). Association of Nterminal probrain natriuretic peptide with cognitive function and depression in elderly people with type 2 diabetes. Chinese Medical Journal 130, 542-548.

Glassman A, Bigger T, Gaffney M (2009). Psychiatric Characteristics Associated With Long-term Mortality Among 361 Patients Having an Acute Coronary Syndrome and Major Depression: Seven-Year Follow-up of SADHART Participants. Archives of General Psychiatry 66, 1022-1029.

Glassman A (2007). Depression and cardiovascular comorbidity. Dialogues in Clinical Neuroscience 9, 9-17.

Gold P, Machado-Vieira R, Pavlatou M (2015). Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress. Neural Plasticity 2015

James SK, Lindahl B, Siegbahn A, Stridsberg M, Venge P, Armstrong P (2003). N-terminal probrain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease: A Global Utilization of Strategies To Open occluded arteries (GUSTO) IV substudy. Circulation 108, 275-281

Khawaja I, Westermeyer J, Gajwani P, Feinstein R (2009). Depression and coronary artery disease: The association, mechanisms, and therapeutic implications. Psichiatry 6 p38-51.

Kronish I, Rieckmann N, Schwartz J, Schwartz D, Davidson K (2009). Is Depression After an Acute Coronary Syndrome Simply a Marker of Known Prognostic Factors for Mortality?. Psichosomatic Medicine 71, 697-703.

Kukreja D, Gunther U, Popp J (2015). Delirium in the elderly: current problems with increasing geriatric age. Indian Journal of Medical Research 142, 655-662

Lahariya S, Grover S, Bagga S, Sharma A (2014). Delirium in patients admitted to a cardiac intensive care unit with cardiac emergencies in a developing country; incidence, prevalence, risk factor and outcome. General Hospital Psychiatry 36, 156-164

Lanas F, Potthoff S, Mercadal E, Santibáñez C, Lanas A, Standen D (2008). Individual and population risk in acute myocardial infarction: The Chilean INTERHEART study. Rev. med. Chile. 136, 555-560

Leifheit-Limson EC, Reid KJ, Kasi SV, Lin H, Bunchanan DM, Jones PG, Peterson PN, Parashar S, Spertus JA, Lichtman JH (2012). Changes in social support within the early recovery period and outcomes after acute myocardial infarction. Journal of Psychosomatic Research 73, 35–41.

Liu H, Luiten PG, Eisel UL, Dejongste MJ, Schoemaker RG (2013). Depression after myocardial infarction: TNF-a-induced alterations of the blood–brain barrier and its putative therapeutic implications. Neuroscience and Biobehavioral Reviews 37, 561–572

Marano G, Harnic D, Lotrionte M, Biondi-Zoccai G, Abbate A, Romagnoli E, Mazza M (2009). Depression and the cardiovascular system: increasing evidence of a link and therapeutic implications. Expert Review of Cardiovascular Therapy 7, 1123-1147

Montero P, Rueda B, Bermudez J (2012). Relación de la personalidad tipo D y el agotamiento vital con las emociones negativas y el ajuste psicológico a la enfermedad cardiaca. Revista de Psicopatología y Psicología Clínica 17, 93-106

Myers V, Gerber Y, Benyamini Y, Goldbourt U, Drory Y (2012). Post-myocardial infarction depression: Increased hospital admissions and reduced adoption of secondary prevention measures — A longitudinal study. Journal of Psychosomatic Research 72, 5–10

Organización Mundial de la Salud (2015). “Enfermedades cardiovasculares – nota de prensa”. Disponible en http://www.who.int/mediacentre/factsheets/fs317/es/.

Pickering T, Davidson K, Shimbo D (2004). Depression as a Risk Factor for Post-MI Mortality. Journal Of The American College of Cardiology 44, 469-474

Poblete F, Glasinovic A, Sapag J, Barticevic N, Arenas A, Padilla O (2015). Apoyo social y salud cardiovascular: adaptación de una escala de apoyo social en pacientes hipertensos y diabéticos en la atención primaria chilena. Atención Primaria 47, 523-531.

Reed G, Rossi J, Cannon C (2017). Acute Myocardial infarction. The Lancet 389, 197-210

Ren Y, Jia J, Sa J, Oiu L, Cui Y, Zhang Y, Yang H, Liu G (2017). Association between N-terminal proB-type Natriuretic Peptide and Depressive Symptoms in Patients with Acute Myocardial Infarction. Chinese Medical Journal 130, 542-8

Richards SH, Anderson L, Jenkinson CE, Whalley B, Rees K, Davies P, Bennett P, Liu Z, West R, Thompson DR, Taylor RS (2017). Psychological interventions for coronary heart disease. Cochrane Database of Systematic Reviews 4

Roest, AM, Carney RM, Freedland KE, Martens EJ, Denollet J, de Jonge P (2013). Changes in Cognitive versus Somatic Symptoms of Depression and Event-Free Survival Following Acute Myocardial Infarction in the Enhancing Recovery In Coronary Heart Disease (ENRICHD) Study. Journal of affective disorders 149, 335–341

Sheps D, McMahon R, Becker L, Carney R, Freedland K, Cohen J, Sheffield D, Goldberg D, Ketterer M, Pepine C, Raczynski J, Light K, Krantz D, Stone P, Knatterud G, Kaufmann P (2002). Mental Stress-Induced Ischemia and All-Cause Mortality in Patients With Coronary Artery Disease: Results From the Psychophysiological Investigations of Myocardial Ischemia Study. Circulation 105, 1780-84.

Swenson JR, Doucette S, Fergusson D (2006). Adverse cardiovascular events in antidepressant trials involving high-risk patients: a systematic review of randomized trials. The Canadian Journal of Psychiatry 51, 923-29

Williams L, O’Connor RC, Grubb NR, O’Carroll RE (2011). Type D personality and illness perceptions in myocardial infarction patients. Journal of Psychosomatic Research 70, 141–144

Zuidersma M, Conradi HJ, van Melle JP, Ormel J, de Jonge P (2013 a) Depression treatment after myocardial infarction and long-term risk of subsequent cardiovascular events and mortality: A randomized controlled trial. Journal of Psychosomatic Research 74, 25–30

Zuidersma M, Conradi HJ, van Melle JP, Ormel J, de Jonge P (2013 b). Self-reported depressive symptoms, diagnosed clinical depression and cardiac morbidity and mortality after myocardial infarction. International Journal of Cardiology 167, 2775–2780




DOI: http://dx.doi.org/10.11565/arsmed.v42i2.656



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